(Esomeprazole Magnesium)

Brand Names: Nexium, Esomeprazole Strontium
Related Medications: Aciphex, Axid, Dexilant, Omeclamox-Pak, Pepcid, Pepcid Injection, Prevacid IV, Prilosec, Protonix, Protonix IV, Tagamet, Yosprala, Zegerid

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Nexium is a trading name of the active ingredient Esomeprazole. This ingredient has a unique ability to slow the production of the basal and stimulating discharges of the gastric acid. An excessive secretion of the gastric acid is one of the main causes of ulcers and erosions on the mucous membrane of the gastro-intestinal tract.

Nexium is prescribed for:

  • Combined treatment of gastric ulcer and duodenal ulcers, including those associated with Helicobacter pylori
  • Zollinger-Ellison syndrome and similar conditions that are characterized by hypersecretion of gastric juice
  • Reinstating/maintenance therapy after treatment of reflux esophagitis
  • During the use of nonsteroidal anti-inflammatory drugs to reduce the risk of ulcer formation

The action of Nexium is reversible. As soon as you stop taking tablets, a secretion of the gastric acid is restored. But in case of the affected parts of the mucous, the gastric juice is not dangerous until an initiating agent appears.

Patients taking drugs for the reduction of the gastric secretion often have a formation of the glandular cysts in the stomach. The use of Nexium does not increase a risk of the neoplasms in the gastro-intestinal tract, and therefore its pharmacological safety is higher than in its analogues.

In what dose is Nexium used?

A tablet of Nexium is used orally, without chewing it, and with enough water. Do not take the tablets with juice or milk because it may affect the cover of the tablet.

  • If reflux esophagitis, it is necessary to take a tablet of Nexium 40 mg per day within a month. During a maintenance therapy, a dose of Nexium may be reduced up to 20 mg and the treatment may last within 3-4 months
  • If ulcers of stomach and duodenum, Nexium 20 mg is used 1-2 times per day within 10-14 days
  • If the gastric ulcer is caused by helicobacter pylori, Nexium 20 mg is used once per day in addition to the antibacterial therapy
  • To treat Zollinger-Ellison syndrome, Nexium 40 mg is used 2 times per day within a long time
  • The use of Nexium may cause an allergic reaction in patients with genetic/acquired intolerance of fructose
  • Nexium is not prescribed children under 14 years old, during severe renal failure, and pregnant women
  • Using Nexium hides the symptoms of the malignant neoplasms, and this may complicate diagnostics. Therefore it is necessary to have a medical examination and eliminate cancerous tumors before the treatment
Side effects

Headache, stomachache, diarrhea, bloating, nausea, vomiting, constipation are the side effects appeared in some cases. They are usually light or moderate.

Some side effects in the gastro-intestinal tract are often associated with Nexium but in fact these reactions may happen during the affection of the organs of the gastro-intestinal tract. Therefore, it is necessary to follow your state and consult a doctor if negative symptoms appear.


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