(Rizatriptan Benzoate)

Brand Names: Maxalt, Maxalt-MLT
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Maxalt is a trading name of the active ingredient Rizatriptan. This ingredient quickly and almost completely (by 90%) is absorbed from the gastro-intestinal tract and may reduce a migraine attack within 20 minutes.

During an episode, people feel really sick because migraine may be accompanied by unbearable headache, dizziness, temporal loss of vision, nausea, vomiting, and increase of the body temperature. Therefore it is very important to stop a migraine attack and relieve a patient’s state.

According to the results of the medical studies, Maxalt copes with its task by 70-80%. About 80% of people experience a complete relief and a reduction of the migraine symptoms in 1-1,5 hours after the use of a therapeutic dose of Maxalt. In some cases, late effects such as heaviness in the head, fatigue, light headache are possible but they do not bring physiological or moral discomfort.

Maxalt stimulates serotonin 5-НТ1d – receptors and stops edema of the vessels in the brain when migraine appears. An origin of migraine is not completely clear, and so an exact mechanism of the Maxalt action is also not available.

Maxalt acts during the attack only. Then, it is excreted from the body, is not accumulated in the tissues, and therefore it does not cause a medical addiction.

In what dose is Maxalt used?

If you have the first signs of migraine, take a tablet of Maxalt 10 mg as soon as possible. A tablet is used with a full glass of water. Try to distract yourself from work or family things within 15-20 minutes. It is better to hole up in dark room, so that none visual or acoustic factors cause an outbreak.

The action of Maxalt grows with the increase of the attack. A peak of the activity of Rizatriptan coincides with a peak of the migraine attack. If you still have severe headache and within 2 hours after the use of the Maxalt tablet 10 mg and do not have any positive effects, you may take another tablet. It is allowed to take 3 tablets of Maxalt 10 mg with the interval of 2 hours.

  • If you are taking propranolol as a basic prevention of migraine, a onetime dose of Maxalt should be reduced up to 5 mg, and daily dose – up to 15 mg
  • Do not use Maxalt with MAO inhibitors. Do not consume alcohol within 24 hours after the use of the tablet
  • If you had a myocardial infarction or stroke within the past 12 months, the use of Maxalt is not recommended
  • If you are diagnosed ischemic heart disease, or this impairment is suspected, the use of Maxalt is contraindicated
  • A safety of Maxalt is not examined in pregnant women and children, and so they do not take the medicine to treat migraine
Side effects

Even though Maxalt reduces headache during migraine, it may cause side effects: sleepiness, lack of energy, high fatigue, severe heartbeat, dyspepsia, and tremor of extremities.

It is impossible to predict an individual reaction of a human to the use of Maxalt, and therefore follow your health after the use of the tablet. Consult a doctor or pharmacist if the side effects appeared.


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